Welcome to Dan
Mulkey's Lab
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| Research Summary |
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My
research is
centered understanding the electrophysiological characteristics of
mammalian neurons in brainstem regions associated with respiratory
control. We are currently using a combination of slice-patch
electrophysiology, fluorescent imaging and genetic approaches to
identify ion channels that regulate activity and neurotransmitter
modulation of respiratory chemoreceptors (i.e., neurons that provide a
CO2/H+-dependent drive to breathe)[project 1]. We are also
interested in the
contribution of astrocytes to respiratory control, specifically we are
exploring how astrocytes sense changes in CO2/H+ and communicate with
neurons and vasculature via a purinergic dependent mechanism [project
2]. A
third research project explores the mechanisms by which nitric oxide
regulates motoneuron activity [project 3].
Teaching Courses:
PNB 2275 Enhanced Physiology and Anatomy Undergraduate Spring PNB 5302 Fundamentals of Physiology Graduate Spring |
University of Connecticut
Department of
Physiology
and Neurobiology
Pharmacy Building, Rm216
(Lab) 860-486-5572